Tightening responses by TIGIT
نویسندگان
چکیده
منابع مشابه
TIGIT negatively regulates inflammation by altering macrophage phenotype.
Macrophages function as an essential component of innate immune system, contributing to both the initiation and appropriate resolution of inflammation. The exposure of macrophages to the microbial products, such as lipopolysaccharide (LPS), can strongly shift the balance between tissue homeostasis and inflammation in favor of causing systemic damage, in which macrophage M1 polarization play imp...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2009
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri2482